United States’ (US) PEPFAR Memorandum of Understanding (PEPFAR MOU)

Policy Brief 150, 12 December 2025

The US Bilateral Specimen Sharing Agreement in the Proposed PEPFAR MOUs Would Leave African Countries More Vulnerable in the Next Pandemic

By Nirmalya Syam, Viviana Munoz Tellez

This Policy Brief examines the implications of the United States’ (US) PEPFAR Memorandum of Understanding (PEPFAR MOU) proposed to African countries on the negotiations for a multilateral system for access to pathogens and benefit sharing (PABS) as part of the World Health Organization’s (WHO) Pandemic Agreement. It recommends that African countries do not accept the MOU provisions on specimen sharing and data access that undermine national sovereignty and calls for a coordinated regional response.

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