Analysis of the European Union Proposal on the Pandemic Agreement Annex dated 17 October 2025
South Centre
This note is prepared to provide South Centre Member States and other developing country delegations with analytical comments on the proposal of the European Union (EU) on the Annex to the Pandemic Agreement, implementing the Pathogen Access and Benefit Sharing (PABS) System as established in Article 12. The note begins with general commentary on the proposal, followed by detailed analysis of the EU proposal text, which is marked in red below the transcribed text.
Participation of South Centre Member Countries in the WHO GLASS: Progress and Gaps in AMR Surveillance and Stewardship Efforts
By Dr. Rasha Abdelsalam Elshenawy
This study highlights antimicrobial resistance (AMR) surveillance challenges in LMICs, focusing on the 55 South Centre Member States’ enrolment in the WHO Global Antimicrobial Resistance and Use Surveillance System (GLASS). Despite progress since its 2016 launch, significant gaps persist: only 60 percent of South Centre Member States report AMR surveillance to GLASS, and just 38 percent report antimicrobial use (AMU) data to GLASS. The COVID-19 pandemic substantially disrupted surveillance activities, with rates declining from 2020-2021 compared to pre-COVID-19 pandemic levels. Digital infrastructure, such as mobile reporting tools, cloud-based systems, and interactive dashboards, offers significant opportunities to strengthen AMR surveillance in resource-limited settings. The study recommends a holistic and phased approach for South Centre Member States, including developing integrated national AMR action plans with realistic implementation timelines, investing in laboratory and workforce development, establishing interoperable digital infrastructure, and strengthening regional collaboration mechanisms. By systematically addressing core surveillance challenges while strategically incorporating digital innovations where appropriate, countries can develop resilient monitoring systems that support effective stewardship, protect national populations, and contribute to global health security by preserving antimicrobial effectiveness for future generations.
The GUIDE Framework for Evidence-based Antibiotic Prescribing
Strengthening Antimicrobial Stewardship for the Healthcare Workforce
By Dr. Rasha Abdelsalam Elshenawy
Antimicrobial resistance (AMR) poses a critical threat to global health security, with inappropriate antibiotic prescribing in hospitals driving the spread of resistant pathogens. This GUIDE Framework for Evidence-Based Antibiotic Prescribing provides a structured, five-step model designed to strengthen antimicrobial stewardship (AMS) and empower the healthcare workforce to make informed, proportionate prescribing decisions.
Co-organized by the National Commission on International Trade & Health Studies (NCITHS), Thailand together with the International Trade & Health Programme (ITH), South Centre & other partners
This book presents reflections and research that highlight tensions in the negotiations on pandemic preparedness treaties and revisions to the International Health Regulations, underscoring the geopolitical divide between developed and developing countries. It advocates regional health initiatives as a response to the multilateral impasse and reflects on the erosion of foundational public health concepts such as “essential medicines”.
New pandemics are inevitable. How can we best prepare for them and, above all, how can we avoid the mistakes and injustices made during the COVID-19 pandemic?
How can equitable access to medicines and diagnostics be guaranteed when they are produced in a small number of countries? How can we explain the fact that current funding for cooperation in the field of health is in the hands of a small group of Northern countries and foundations from the North? How can the role of the World Health Organization be strengthened? WHO now plays only a minor role in coordinating public health policies. How is it that the concept of “essential medicines”, a major advance in public health policy, is being replaced by that of “medical countermeasures”, a term more in line with the private sectors?
Preparing for future pandemics forces us to ask ourselves: how can we safeguard the general interest, the defense of human rights and public health?
Negotiating Global Health Policies: Tensions and Dilemmas is essential reading for negotiators from the 194 member countries of the World Health Organization (WHO), the World Trade Organization (WTO), and the World Intellectual Property Organization (WIPO) who participate in international negotiations on health and development. Academics and students of medicine, health sciences, law, sociology and political science, as well as intergovernmental organizations and non-governmental organizations who work on access to medicines and global health issues, also would find the book of interest.
Author: Germán Velásquez is Special Adviser, Policy and Health of the South Centre in Geneva, Switzerland. Previously, he was Director of the Secretariat on Public Health, Innovation and Intellectual Property at WHO. He represented WHO at the WTO TRIPS Council from 2001 to 2010. He is the author and co-author of numerous publications on health economics and medicines, health insurance schemes, globalization, international trade agreements, intellectual property and access to medicines.
He obtained a Master’s degree in Economics and a PhD in Health Economics from Sorbonne University, Paris. In 2010, he received a Honoris Causa PhD on Public Health from the University of Caldas, Colombia and in 2015 he received another Honoris Causa PhD from the Faculty of Medicine of the Complutense University of Madrid, Spain.
Designing an Independent Panel onEvidence for Action on Antimicrobial Resistance: Lessons from Selected Bodies in Global Health, Climate Change and Biodiversity
By Viviana Munoz Tellez and Francesca Chiara
This paper proposes a framework for designing an Independent Panel on Evidence for Action on Antimicrobial Resistance (IPEA), responding to the 2025 United Nations General Assembly mandate. Through a comparative analysis of selected international scientific advisory bodies, we identify the panel’s mandate as the foundational element that will critically shape its composition, scope, deliverables, and governance structure. Our framework addresses key domains of credibility, scientific integrity, authority, policy relevance, and sustainability while establishing equity as a fundamental design principle—not merely ensuring low and middle-income country (LMIC) participation but designing the IPEA to address existing imbalances in antimicrobial resistance (AMR) evidence production and dissemination. We analyse potential mandate options, from evidence synthesis to policy recommendations, highlighting the importance of defining a unique and complementary role for IPEA within the existing AMR governance landscape to avoid duplication and maximize impact on global AMR response.
INTERNSHIP PROGRAMME – STRENGTHENING THE RIGHT TO HEALTH
The South Centre is seeking to fill internship positions to support its activities in the area of strengthening the right to health from a perspective of countries of the Global South.
Specific intern responsibilities include, but are not limited to, supporting the Strengthening the Right to Health project.
Statement of the Executive Director of the South Centre, Dr. Carlos Correa, at the NAM Health Ministers’ Meeting on the sidelines of the 78th World Health Assembly (May 19-27, 2025)
The decisions to be made at the 78th World Health Assembly will have direct implications not only for national health systems, but also for the very architecture of international cooperation in health. Read the statement by the Executive Director of the South Centre, Dr. Carlos Correa, at the NAM Health Ministers’ Meeting on the sidelines of the 78th WHA.
Leaving the WHO? The US Just Shot Itself in the Foot
By Germán Velásquez
At the start of his second term, United States president Donald Trump has again announced that the US will formally leave the World Health Organization (WHO) in 2025. Leaving the WHO is a financial blow to the Organization, as many have pointed out, but it is much more than that. Trump’s decision to abandon WHO is counterproductive and puts at risk the capacity of the organization to perform its role as the global health agency. The WHO has been central to responding to global health emergencies for more than seven decades. Its work in the fight against diseases such as smallpox, polio, Ebola and HIV/AIDS, or the binding international convention against tobacco use, has saved millions of lives.
The US’ withdrawal from WHO will have a serious impact on various aspects of global health, and the US will itself be directly affected. WHO members should unite to strengthen the WHO and counteract this decision by the current US Administration.
South Centre Statement to the Resumed Thirteenth Meeting of the Intergovernmental Negotiating Body to Draft and Negotiate a WHO Convention, Agreement or Other International Instrument of Pandemic Prevention, Preparedness and Response
7 April 2025
Negotiations resume for a WHO pandemic agreement, aiming to finalise the text in 5 days. Will Member States show the needed leadership and will to deliver an impactful outcome with equity at the core?
Strengthening Antimicrobial Stewardship Policy: Insights from COVID-19 and Future Pandemic Preparedness
South Centre Webinar
Date: 14 April 2025 Time: 12:00 PM – 1:00 PM CEST | 6:00 AM – 7:00 AM EDT | 3:30 PM – 4:30 PM IST Location: Virtual (Zoom)
In this one-hour webinar, we will explore how the COVID-19 pandemic impacted antimicrobial stewardship (AMS) programmes and what lessons can strengthen future pandemic preparedness, especially in low- and middle-income countries (LMICs).
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