Health

South Centre Report, October 2024

Group of 77 and South Centre convening on the Future of Antimicrobial Resistance Response in Developing Countries

Meeting Report

October 2024

On 25 September, the South Centre with the Group of 77 and China discussed solutions for tackling Antimicrobial Resistance and ensuring access to antibiotics and diagnostics.

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Science in crisis times, 22 October 2024

Science in crisis times: The crucial role of science in sustainability and transformation

PLOS Sustainability and Transformation Journal

Authors: Paul Shrivastava, Louise Jackson, Thaura Ghneim-Herrera, Patrick Caron, Carlos Correa, Carlos Alvarez Pereira, Timothy Coombs, Oluchi Ezekannagha, Nick Ishmael-Perkins, Melissa Leach, Sélim Louafi, Gary E. Machlis, Julia Marton-Lefèvre, Alexander Müller, Janos Pasztor, Vivi Stavrou, Camilla Toulmin, and Sonja Vermeulen

In an era marked by the convergence of complex crises, the role of science in sustainability and transformative changes has never been more critical. A recent article in PLOS Sustainability and Transformation Journal, titled “Science in Crisis Times: The Crucial Role of Science in Sustainability and Transformation,” delves into this pressing issue. Authored by a distinguished group of experts, including former MAK’IT Scientific Officer Thaura Ghneim-Herrera and South Centre Executive Director Carlos M. Correa, the article draws from the insights of the 2022 MAK’IT conference “What Role for Science in Crisis Times? Outlook in the Health, Environment, and Agriculture Interconnected Areas”, held in University of Montpellier with the support of the South Centre, which brought together 18 international experts.

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SC Statement to the High-Level Meeting on AMR, September 2024

Statement of the South Centre to the High-Level Meeting on AMR

September 2024

The South Centre is committed to support developing countries in tackling antimicrobial resistance. We welcome the opportunity to speak to this Assembly and add our voice to the call for urgent action to tackle this global threat. This year must mark the turning point in the collective efforts backed by new commitments and targets.

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Research Paper 209, 25 September 2024

AMR in Aquaculture: Enhancing Indian Shrimp Exports through Sustainable Practices and Reduced Antimicrobial Usage  

By Robin Paul

This study on Antimicrobial Resistance (AMR) in Indian shrimp farming underscores its critical impact on public health, environmental sustainability, and economic viability. The global scenario with many export rejections on account of persistent residues of antibiotics, reiterate that antimicrobial use in aquaculture, demands urgent global attention.

In the Indian context, the shrimp industry grapples with a delicate balance between production demands and long-term shrimp health. Sustainable practices, including responsible antimicrobial use, are crucial for economic viability, given the industry’s reliance on specific markets like the United States, EU and China.

Sustainable aquaculture emerges as a pivotal solution, supported by government policies and a gradual industry shift towards best practices. However, challenges persist, requiring a comprehensive approach to balance economic interests with environmental conservation. The key challenges remain the large number of small stakeholders and huge geographical spread of farms which make implementation of regulations and sharing of best practices difficult. Traceability and certification programs can play a key role in promoting responsible aquaculture, ensuring transparency and accountability in the supply chain. Technological innovations, including block chain can offer efficient solutions for traceability.

The collaborative action suggested emphasizes the role of government bodies, regulatory agencies, industry players, researchers, and consumers in addressing AMR. Clearer implementable regulatory frameworks aligned with economic and environmental priorities are essential. Looking ahead, the study envisions a future where the blue economy is sustainable not just for the industry’s success but also to protect the wider environment. By enhancing domestic market presence and fostering collaboration with importing countries, the Indian industry can overcome the multiple challenges raised by AMR in shrimp aquaculture.

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Research Paper 206, 28 August 2024

Equity and Pandemic Preparedness: Navigating the 2024 Amendments to the International Health Regulations  

By Nirmalya Syam

The amendments to the International Health Regulations (2005) (IHR) agreed upon in May 2024 are important for strengthening global health emergency preparedness and response. The negotiations resulted in the IHR amendment now recognizing the importance of equity, including equitable access to health products, enhancing IHR core capacities, and mobilizing financing. The amendments note the role of the World Health Organization (WHO) in facilitating timely access to necessary health products by removing barriers and supporting local production and distribution. However, the WHO authority to effectively act in those areas is limited. The IHR as amended will establish a Coordinating Financial Mechanism to provide predictable and sustainable financing for its implementation, particularly in developing countries.

Despite some advancements, the amendments fall short of imposing concrete obligations on developed countries to facilitate timely access to health products and financial support and transfer of technology to developing countries. Overall, the amended IHR represent a significant step toward a more equitable global health framework, setting a precedent for future international health instruments, including the proposed pandemic treaty.

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Research Paper 204, 24 July 2024

Negotiating Health and Autonomy: Data Exclusivity, Healthcare Policies and Access to Pharmaceutical Innovations

By Henrique Zeferino De Menezes, Julia Paranhos, Ricardo Lobato Torres, Luciana Correia Borges, Daniela De Santana Falcão and Gustavo Soares Felix Lima

This paper analyzes the debate over the international dissemination of data exclusivity as a form of protection for clinical trial data. This is a critical demand for pharmaceutical companies seeking larger market shares and longer periods of monopoly in order to recover investments in research and development and greater profitability. However, this is a sensitive issue with economic and social repercussions for developing countries that adopt this protection regime. This paper highlights critical issues for the political economy of innovation and presents a review of empirical studies that show that data exclusivity delays the entry of generic drugs into the market, increasing prices and reducing access. At the same time, its adoption has no benefits because there are no positive effects on internal technological innovation, nor reduction of the “International drug lag”, nor the development of drugs for specific epidemiological demands.

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Research Paper 203, 11 July 2024

The Vaccine Industry After the COVID-19 Pandemic: An International Perspective

By Felix Lobo

The purpose of this report is to analyze the impact that the COVID-19 pandemic has had on the vaccine industry from an international perspective. The objective is to learn from the experience and contribute to the design of better tools for future vaccine development and manufacturing, as we must be prepared for future emerging infectious diseases with the potential for global expansion. This industry makes fundamental contributions to global social welfare, but from a business point of view it is complex and difficult to manage, and from an economic point of view it is an industry that does not fit the paradigm of competitive market efficiency with notorious market failures.

We examine the impact of the pandemic on innovation and the scientific, technological and industrial development of vaccines and find that certain elements of the industry’s structure have changed, while others have remained. We also summarize the lessons learned from the deployment of some public policies to boost supply and drive demand, paying particular attention to the inequity in the global distribution of vaccines and to the COVAX program. We conclude that some of the policies have been very effective, while others have not fully achieved their objectives. From the achievements and limitations, lessons can be drawn for the reformulation and expansion of global public policies that would stimulate R&D, manufacturing, distribution and access.

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Research Paper 202, 28 June 2024

Constraints to and Prospects for Sustainable Livestock Sector Practices in Argentina with Emphasis on Antimicrobial Usage

By David Oseguera Montiel

Antimicrobial resistance (AMR) is a top threat for global health and development as it has the potential to become the next pandemic. Agriculture roughly accounts for three-quarters of all the antimicrobial usage. Modern animal husbandry systems use antimicrobials for disease prevention and growth promotion. Regulations and restrictions regarding antimicrobial use in agriculture vary across the regions of the world. This paper explores the situation of the Argentina livestock sector with regard to antimicrobial use. Argentina is renowned as a global food producer, notably for its grain and livestock production potential. This paper analyzes the constraints to and prospects for transitioning towards a more sustainable livestock farming production in Argentina by relying less on antimicrobials and without compromising productivity. The livestock sector in Argentina has embarked on the intensification of farming, especially beef farming, in the last thirty years. Farming intensification generally requires the use of greater quantities of antibiotics. Alternative sustainable intensification is necessary to overcome antimicrobial overuse. Various factors, including economic, social, and cultural, shape consumption patterns. The Argentine farming sector needs to focus on these context-specific situations, which will drive animal food production.

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Research Paper 201, 27 June 2024

Antimicrobial Resistance: Optimizing Antimicrobial Use in Food-Producing Animals

 By Viviana Munoz Tellez

The increasing resistance of microorganisms to antimicrobials that help to treat and control spread of infections is a major public health problem around the world. Antimicrobial resistance is aggravated by inappropriate use of antimicrobials in human and animal health and in plant and animal agriculture. This paper tackles the question of how to shift animal food production to implement adequate antimicrobial stewardship practices.

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South Centre Statement – IHRs 2005 Amendment, May 2024

Statement on the Amendment to the International Health Regulations

We congratulate the WHO members for the adoption of the  amendments to the International Health Regulations to advance equity in access to health products, increase collaboration and finance to develop, strengthen and maintain core capacities. Efforts must continue to finalise a pandemic treaty.

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