Three Decades of Global Engagement: The South Centre’s Contribution to Intellectual Property and Development
By Nirmalya Syam
South Centre 30th Anniversary Series No. 2, 30 April 2026
This paper is part of a series of publications made in commemoration of the 30th anniversary of the South Centre, an intergovernmental organization established in 1995 to advance the interests of developing countries in global governance. Tracing its origins to the 1990 South Commission, it examines the Centre’s pivotal role in shaping intellectual property (IP) policies to promote equitable development. Through rigorous research, advocacy, and technical assistance, the South Centre has supported negotiations at the World Intellectual Property Organization (WIPO) and World Trade Organization (WTO), influencing milestones like the 2007 WIPO Development Agenda and extensions of the Agreement on Trade-Related Aspects of Intellectual Property Rights (TRIPS) transition periods for least developed countries.
Key contributions include promoting TRIPS flexibilities for public health, biodiversity, and technology transfer, with seminal publications on compulsory licensing, patent examination, and traditional knowledge protection. During the COVID-19 pandemic, the Centre advocated for IP waivers to enhance access to vaccines and therapeutics. Impacts include empowering Global South nations to implement development-oriented IP strategies and reform patent laws. Looking ahead, the paper addresses challenges from digital transformation, artificial intelligence (AI), and data governance, calling for strengthened South-South cooperation and proactive advocacy to ensure inclusive IP frameworks. The South Centre remains essential for fostering sustainable development and reducing global inequalities.
Evidence of Partnerships in the Cuban Pharmaceutical Sector
By Graziela Ferrero Zucoloto
This article analyzes the pharmaceutical partnership agreements of Cuban institutions. It identifies various partnerships with national and foreign firms that spanned 17 countries, with several developed nations appearing as recipients of Cuban technologies, and with Cuban institutions acting as the primary technology holder and licensor in the majority of agreements identified. These findings suggest that Cuba’s state-directed pharmaceutical model has produced an active, innovation-generating sector, with potential lessons for other countries, including Brazil, that maintain public pharmaceutical laboratories.
Statement by the South Centre to the WIPO Assemblies on the Reappointment of the Director General, Daren Tang
21 April 2026
The South Centre looks forward to a further engagement of WIPO Director General Daren Tang during his second term with the development dimension of intellectual property.
In our statement to the WIPO Assemblies on 21 April, we highlight priorities that should be included in the new Medium-Term Strategic Plan. These include: prioritize development, technology transfer, fee reductions for developing countries and LDCs, and a broader focus on innovation, not only on the role of IP.
The South Centre carries out multiple activities to support developing countries with policy-oriented research, inputs and advice for negotiations and capacity building. The Report summarizes the South Centre’s activities in 2025 and highlights the contexts in which they were conducted as well as the objectives that were pursued with their implementation.
Inputs to UN CSTD Working Group on Data Governance at All Levels
Track 3 – Considerations of Sharing the Benefits of Data
South Centre
February 2026
The South Centre submission to the United Nations Working Group on Data Governance highlights how economic and social benefits of data can accrue more equitably to the people and countries of the Global South.
Unlocking Innovation Traps: A Systems Thinking Approach to University–SME Collaboration
By Dr. Ufuk Türen and Syed Ibrahim Bilal Majid
Despite growing institutional interest, university–small and medium-sized enterprise (SME) collaborations often underperform, stalling before generating sustainable innovation. This study adopts a systems thinking perspective to diagnose such persistent failures as structural—rather than individual—challenges. Using OSTİM Technical University (OSTİMTECH) as a case study, the research employs participatory causal loop diagrams (CLDs) to visualize key feedback dynamics affecting trust, incentives, and knowledge flows. Central to the analysis is the “Success to the Successful” archetype, which explains how dominant academic incentives reinforce publication-oriented behaviors while marginalizing collaboration and applied innovation. The resulting model reveals why certain loops—like academic reputation—gain momentum while others—such as ecosystem learning—remain underdeveloped without intentional redesign. By identifying leverage points for institutional reform, including incentive recalibration and long-term partnership support, the paper offers actionable insights for third-generation universities. Ultimately, reframing collaboration through a systemic lens enhances understanding of complex innovation ecosystems and guides more credible, sustainable approaches to university–industry engagement.
Towards a Development-Oriented TRIPS Review Under Article 71.1
By Nirmalya Syam
This paper calls for a comprehensive, development-focused review of the Agreement on Trade-Related Aspects of Intellectual Property Rights (TRIPS Agreement) under Article 71.1, a process that has been mandated but never carried out. It critiques the narrow, compliance-driven approach favored by developed countries, which risks sidelining the broader developmental objectives enshrined in Articles 7 and 8 and reaffirmed by the Doha Declaration on the TRIPS Agreement and Public Health. Through a detailed analysis of the political context, procedural history, and legal mandates, the paper argues that the TRIPS review should center on the real-world impact of the Agreement on developing countries—particularly in areas such as public health, access to medicines, technology transfer, and innovation capacity. It proposes an impact assessment framework grounded in empirical indicators to evaluate how TRIPS has influenced public welfare, policy space, and economic development. Ultimately, the paper urges the World Trade organization (WTO) to fulfill its long-overdue obligation to reassess TRIPS not as a compliance checklist but as a living instrument that must align with global equity and development goals.
From Fragmentation to Impact: Strengthening Southern Agency in Global AI Governance
By Vahini Naidu and Danish
Artificial Intelligence (AI) is transforming production, trade and governance systems, yet global regulatory efforts remain fragmented and uneven. The multiplicity of forums, frameworks and initiatives, from UN processes to plurilateral and trade-centred mechanisms, has produced overlapping agendas and resulted in diminished participation from global South stakeholders. For developing countries, the challenge is to engage meaningfully in global AI governance while preserving national policy space and advancing sustainable development priorities.
This policy brief examines the evolving landscape of AI governance, focusing on its institutional fragmentation and the competing conceptions of regulation advanced through the UN, G20, BRICS, and other fora. It argues that coherent, development-oriented AI governance requires strengthening UN-anchored processes and linking AI regulation to industrial policy, innovation systems and data sovereignty. The brief concludes that inclusive, sustainable and responsible AI governance should support governments in enhancing their capacities to harness AI and emerging technologies to shape their digital transformation.
South Centre in collaboration with IT for Change and Center of Policy Research and Governance, with the support of the Permanent Mission of India to the UN in Geneva
Monday, 17 November 2025, 13:15 – 14:15, Palais des Nations, Room VIII, Geneva
Held in preparation for the AI Impact Summit 2026, this event will discuss how countries can work together to ensure Artificial Intelligence supports inclusive and sustainable development, strengthens national and regional capacities, and promotes equitable participation in global AI governance.
Statement by South Centre at the Ministerial Meeting on Artificial Intelligence, Data Governance and Innovation for Sustainable Development (G20 Task Force)
30 September 2025, Cape Town
The South Centre welcomes the G20’s effort to advance meaningful participation of developing countries in shaping a fair, safe, secure, responsible, inclusive, ethical, trustworthy, and sustainable global AI landscape. Data governance is a foundation for equitable AI. Countries are entitled to develop and adopt regulatory frameworks for AI systems, including to reflect diverse knowledge systems and fair remuneration for data contributions.
International Day of Science, Technology and Innovation for the South
September 16, 2025
Dr. Carlos Correa, South Centre Executive Director, highlighted the transformative role of S&T. He also noted that despite the enormous historical North-South asymmetry in the capacity to generate S&T, developing countries’ share of global R&D has increased steadily in the last two decades, while many countries still invest less than 1% of their GDP in R&D.
The Importance of Balanced Intellectual Property Systems for Patients’ Access to Medicines: An Analysis
By Archana Jatkar and Nicolás Tascón
Access to safe, effective, cost-effective, and quality-assured medicines is fundamental from a patients’ perspective. The International Generic and Biosimilar Medicines Association (IGBA) recently released a reporthighlighting the critical balance between innovation, competition, and timely access to medicines. This article delves into the key findings of IGBA’s report, their implications on patient access to medicines and national healthcare budgets, and the IGBA’s recommendations for improving the global pharmaceutical landscape.
