South Centre Annual Report 2025
The South Centre carries out multiple activities to support developing countries with policy-oriented research, inputs and advice for negotiations and capacity building. The Report summarizes the South Centre’s activities in 2025 and highlights the contexts in which they were conducted as well as the objectives that were pursued with their implementation.
G20 Critical Minerals Deal: A Step Toward Equity or a New Extractive Frontier?
By Touba Esfahani Nejad
This paper examines the Group of Twenty (G20) Critical Minerals Framework adopted under South Africa’s Presidency and the extent to which it represents a shift toward more equitable mineral governance. It analyses the Framework’s key pillars and political commitments alongside the Johannesburg G20 Leaders’ Declaration, assessing their implications for mineral-rich developing countries, importing economies, refining hubs, and the G20 itself. The paper pays particular attention to gaps between stated ambitions and practical constraints having in view financing, technology transfer, and the policy space under the World Trade Organization (WTO) rules. It concludes by identifying the conditions under which the Framework could support real value addition and industrialization in the Global South rather than function as a supply-security tool for advanced economies.
Analysis of Intellectual Property Issues Ahead of the WTO 14th Ministerial Conference
By Nirmalya Syam, Viviana Munoz Tellez
This policy brief analyses the issues pertaining to the World Trade Organization (WTO) Agreement on Trade-Related Aspects of Intellectual Property Rights (TRIPS Agreement) that were discussed in the General Council meeting on 16-17 December 2025. Despite the strategic importance of these issues, the divergence on TRIPS issues and on the priorities for the future work of WTO among Members did not allow the General Council to decide on any of these matters. None of the issues were noted for decision in the 14th Ministerial Conference (MC14), which is scheduled to be hosted in Yaoundé, Cameroon in March 2026. This reluctance of some Members to engage substantively on intellectual property (IP) issues has become a regular dynamic in the TRIPS Council. However, the MC14 should, at the least, decide to extend the moratorium on TRIPS Non-Violation and Situation Complaints and extend the period for acceptances by Members of the Protocol Amending the TRIPS Agreement. Moreover, there is an understanding that all issues remain on the table, regardless of whether they are taken up at the Conference.
South Centre Statement to IGWG5 on the WHO Pandemic Agreement
9 February 2026
The World Health Organization (WHO) Intergovernmental Working Group (IGWG) is reconvening to negotiate a Pathogen Access and Benefit Sharing (PABS) System to make operational Article 12 of the WHO Pandemic Agreement, concluded in May 2025 but requiring conclusion of the PABS to move towards ratifications. The Fifth Meeting of the IGWG (IGWG5) will meet from 9-14 February 2026, and the negotiations are meant to conclude by May 2026.
The South Centre has made a statement to the IGWG5 highlighting the imbalance in the current Bureau text. The statement of the South Centre is reproduced below.
Towards a Development-Oriented TRIPS Review Under Article 71.1
By Nirmalya Syam
This paper calls for a comprehensive, development-focused review of the Agreement on Trade-Related Aspects of Intellectual Property Rights (TRIPS Agreement) under Article 71.1, a process that has been mandated but never carried out. It critiques the narrow, compliance-driven approach favored by developed countries, which risks sidelining the broader developmental objectives enshrined in Articles 7 and 8 and reaffirmed by the Doha Declaration on the TRIPS Agreement and Public Health. Through a detailed analysis of the political context, procedural history, and legal mandates, the paper argues that the TRIPS review should center on the real-world impact of the Agreement on developing countries—particularly in areas such as public health, access to medicines, technology transfer, and innovation capacity. It proposes an impact assessment framework grounded in empirical indicators to evaluate how TRIPS has influenced public welfare, policy space, and economic development. Ultimately, the paper urges the World Trade organization (WTO) to fulfill its long-overdue obligation to reassess TRIPS not as a compliance checklist but as a living instrument that must align with global equity and development goals.
Promoting a Symbiotic Relationship Between Trade Policy and Climate Action
By Vahini Naidu
This paper is based on remarks delivered in the lead up to COP30. It outlines how African countries are working to align trade, climate action, and development priorities through early transparency on climate-related trade measures, technology transfer, and the protection of policy space for green industrialisation. It also highlights the growing focus on critical minerals, the rise of unilateral climate-related trade measures, and the need to bring scattered initiatives into a coherent multilateral framework that supports fair and sustainable outcomes.
From Fragmentation to Impact: Strengthening Southern Agency in Global AI Governance
By Vahini Naidu and Danish
Artificial Intelligence (AI) is transforming production, trade and governance systems, yet global regulatory efforts remain fragmented and uneven. The multiplicity of forums, frameworks and initiatives, from UN processes to plurilateral and trade-centred mechanisms, has produced overlapping agendas and resulted in diminished participation from global South stakeholders. For developing countries, the challenge is to engage meaningfully in global AI governance while preserving national policy space and advancing sustainable development priorities.
This policy brief examines the evolving landscape of AI governance, focusing on its institutional fragmentation and the competing conceptions of regulation advanced through the UN, G20, BRICS, and other fora. It argues that coherent, development-oriented AI governance requires strengthening UN-anchored processes and linking AI regulation to industrial policy, innovation systems and data sovereignty. The brief concludes that inclusive, sustainable and responsible AI governance should support governments in enhancing their capacities to harness AI and emerging technologies to shape their digital transformation.
Submission by the South Centre
International Day of Science, Technology and Innovation for the South
September 16, 2025
History of the Negotiations of the TRIPS Agreement
By Carlos Correa
When the currently developed countries started their industrialization process, the intellectual property system was very flexible and allowed them to industrialize based on imitation, as it was notably the case of the United States. The international intellectual property system evolved since the end of the XIX Century based on a number of conventions on which the Agreement on Trade-Related Aspects of Intellectual Property Rights (TRIPS Agreement) was later built on. Developing countries resisted the incorporation into the Uruguay Round of the General Agreement on Tariffs and Trade (GATT) of broad disciplines on intellectual property, as they were conscious that they were disadvantaged in terms of science and technology and that a new agreement, with a mechanism to enforce its rules, would freeze the comparative advantages that developed countries enjoyed. Faced with the threat of not getting concessions in agriculture and textiles -that were crucial for their economies- they were finally forced to enter into negotiations of an Agreement, the terms of which were essentially dictated by developed countries. Coercion rather than negotiations among equal partners seems to explain the final adoption of this Agreement.
Advancing International Cooperation under the Global Digital Compact
By Danish
Bridging the global digital divide in new and emerging technologies, particularly Artificial Intelligence, will require developing countries to strongly leverage international cooperation to build digital skills, knowledge and gain access to these technologies which can accelerate their digital transformation and sustainable development. This emphasis on international cooperation is also deeply embedded in the Global Digital Compact, which was adopted as part of the Pact for the Future. This paper therefore looks at how international cooperation modalities have been included in the GDC across the different issue areas, how developing countries are already engaging with the GDC through their national initiatives, and provides some useful considerations going forward.
Leveraging the Antimicrobial Resistance Declarations of 2024 to Reduce the Burden of Drug-Resistant Infections
By Afreenish Amir & Viviana Munoz Tellez
In 2024, two significant events highlighted the global concern about antimicrobial resistance (AMR). AMR is a pressing global health issue, imperiling public health, economic stability, and societal well-being. The 79th United Nations General Assembly (UNGA) in its special session on AMR and the 4th Ministerial Meeting on AMR have emphasized the need for collective action and international cooperation to mitigate the impact of AMR. The UNGA Declaration has set some targets including reducing global deaths associated with bacterial AMR by 10% by 2030 and enhancing the antimicrobial usage from the World Health Organization (WHO) AWaRe (Access, Watch, Reserve) Access category to 70% by 2030. Accomplishing these targets requires enhancing the inter-ministerial and inter-sectoral collaboration within countries, and the development of strategies reflected in national action plans (NAPs) tailored to each country’s unique dynamics. There are several important commitments made that now need to be implemented, including increased support to countries to develop funded NAPs, the establishment of an Independent Panel on Evidence for Action against AMR, capacity building for local manufacturing of vaccines, therapeutics, diagnostics and essential supplies, developing a new Global Action Plan on AMR by 2026 with a focus on a people centered approach, and advancing cross-sectoral behavioral change interventions. However, these fell short of ambition, particularly in key areas such as financing, reduction of misuse and overuse of antimicrobials in human and animal health and the environment as a vector for AMR. This Policy Brief reviews the new commitments on AMR made in 2024 under the light of current challenges in developing countries and advances recommendations to accelerate progress on AMR.
South Centre Annual Report 2024
The South Centre carries out multiple activities to support developing countries with policy-oriented research, inputs and advice for negotiations and capacity building. The Report summarizes the South Centre’s activities in 2024 and highlights the contexts in which they were conducted as well as the objectives that were pursued with their implementation.
