In Focus

Climate Policy Brief 29, 14 November 2025

Leveraging the ICJ Opinion to Secure a Just Climate Future for the South during COP30

By Daniel Uribe Terán

The 30th Conference of the Parties (COP30) in Belém converges with the recent International Court of Justice (ICJ) Advisory Opinion on Climate Change, creating a critical inflexion point for global climate action. This policy brief analyses how the ICJ Opinion has the potential to reframe climate commitments, transforming them from political aspirations into legally binding obligations. The Opinion establishes objective standards for ‘due diligence’, integrates the CBDR-RC principle as a legal criterion for ambition, and inextricably links climate action with human rights. The ICJ Opinion confirms that a breach of these obligations triggers a duty of ‘full reparation.’ This policy brief recommends a strategy for developing countries to leverage this new legal framework at COP30.

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SC Webinar – Guidance on Antimicrobial Stewardship, 17 November 2025

Zoom Webinar:

Implementing Evidence-based Antimicrobial Prescribing to Combat AMR and Strengthen Global Stewardship – The GUIDE Framework in Action

Monday, 17 November 2025, 12:00-13:00 CET/11:00-12:00 UK/06:00-7:00 EDT/15:30-16:30 IST

Join us for the launch of a new evidence-based tool to enhance antimicrobial prescribing and stewardship. Share your feedback to help us strengthen its value and usability for global practice.

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SC Guide Framework for Evidence-based Antibiotic Prescribing, November 2025

The GUIDE Framework for Evidence-based Antibiotic Prescribing

Strengthening Antimicrobial Stewardship for the Healthcare Workforce

By Dr. Rasha Abdelsalam Elshenawy

Antimicrobial resistance (AMR) poses a critical threat to global health security, with inappropriate antibiotic prescribing in hospitals driving the spread of resistant pathogens. This GUIDE Framework for Evidence-Based Antibiotic Prescribing provides a structured, five-step model designed to strengthen antimicrobial stewardship (AMS) and empower the healthcare workforce to make informed, proportionate prescribing decisions.

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SC Pre-Summit Event – AI Impact Summit 2026, 17 November 2025

AI Impact Summit 2026 – Pre-Summit Event

Advancing Innovation for Equitable AI Access

South Centre in collaboration with IT for Change and Center of Policy Research and Governance, with the support of the Permanent Mission of India to the UN in Geneva

Monday, 17 November 2025, 13:15 – 14:15, Palais des Nations, Room VIII, Geneva

Held in preparation for the AI Impact Summit 2026, this event will discuss how countries can work together to ensure Artificial Intelligence supports inclusive and sustainable development, strengthens national and regional capacities, and promotes equitable participation in global AI governance.

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Research Paper 226, 12 November 2025

The Taxation of the Digital Economy in Practice: Digital Services Taxes and Other Measures

By Natalia Quiñones, Anchal Khandelwal, Oluwole Olushola Oni, Maryam Maiyaki, Doris Malgwi, Ezekiel Swema, Nickson Omondi, Ivy Watti, Dinesh Thapa, Anne Wanyagathi Maina & Kolawole Omole

Digital businesses continue to grow and generate substantial revenue in market jurisdictions without maintaining a physical presence. They mainly rely on intangibles, user data and user engagement. International tax rules have not kept pace with these developments, leaving many jurisdictions unable to tax digital economic activity effectively. In response, countries have introduced national measures, such as Digital Services Taxes (DSTs), equalisation levies, and Significant Economic Presence (SEP) taxes, while continuing to engage in multilateral efforts. This paper examines how countries have implemented such measures. The study applies structured case studies of Colombia, India, Kenya, Nepal, Nigeria, and Tanzania.  It analyzes the countries’ legal frameworks, administrative practices, and revenue outcomes, while also identifying shared features and key differences in implementation approaches. The paper explores the conceptual foundations and theoretical justifications for taxing digital revenues at source, highlighting the limitations of current profit allocation rules that overlook the role of the market. Drawing from these country experiences, the study develops a peer learning framework based on emerging best practices while recognizing the challenges in implementation. The study then proposes pathways for harmonizing digital tax measures and outlines essential design elements to inform the development of the early protocol on the taxation of cross border services (which includes digital services) under the United Nations Framework Convention on International Tax Cooperation.

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SC BU GDPC Report, November 2025

Report on Compulsory Licensing Provisions in the National Patent Legislation of 15 Middle-Income Countries:

A Content Analysis and Recommendations

A Report of the Global Economic Governance Initiative of the Boston University Global Development Policy Center

Published by the South Centre and the Global Economic Governance Initiative of Boston University Global Development Policy Center

This study examines compulsory licensing laws in 15 middle-income countries often excluded from voluntary licenses & finds significant untapped policy space to advance access to affordable medicines. It highlights best practices & makes key recommendations to improve patent laws for the use of this important TRIPS flexibility.

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South Centre Informal Note, 2 November 2025

WTO Reform: Assessment of the Facilitator’s Communication and Process Ahead of the 4 November 2025 Plenary

An Informal Note Reviewing the Reform Tracks and Process in Advance of the 4 November Plenary, 2 November 2025

By Vahini Naidu, Trade for Development Programme, South Centre

This note provides an analytical assessment of the Facilitator’s Communication and process ahead of the WTO reform plenary held on 4 November 2025. It highlights the growing procedural opacity surrounding the reform process, characterised by informal, facilitator-led configurations that lack clear mandates, participation criteria, or official records of discussions. These methods have blurred the lines between Member-driven deliberation and Secretariat-managed processes, creating uncertainty over accountability, legitimacy and inclusiveness.

Substantively, the Facilitator’s synthesis elevates certain reform tracks, notably decision-making and level playing field, as forward-looking agendas, while confining the Development and S&DT track to a diagnostic or exploratory stage. This imbalance risks entrenching asymmetries rather than addressing them. By conflating S&DT with the broader development mandate, the Communication effectively narrows the systemic development agenda of the Marrakesh Agreement to a limited discussion of differentiation and eligibility.

Read together, the procedural and substantive dynamics reveal a process that is fragmented, imbalanced and at risk of being shaped by informal interpretations rather than by Member-driven decisions. The note calls for restoring transparency, reaffirming the primacy of consensus and re-centring development as the organising principle of WTO reform.

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Webinar – Report Launch, 13 November 2025

Are countries maximizing the policy space they have to grant compulsory licenses to improve access to medicines?

Webinar

Date & Time: Thursday, 13 November 2025, 13h-14h30 (Geneva) / 7h-8h30 (Boston) / 23h-00h30 (Melbourne)

Join the Launch of a Report on Compulsory Licensing Provisions in the National Patent Legislation of 15 Middle-Income Countries, published by the South Centre and the Global Economic Governance Initiative of Boston University Global Development Policy Center.

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SC Report on 66th Series of Meetings of WIPO Assemblies, October 2025

Building Up a Balanced Global Intellectual Property System:  Report of the WIPO Assemblies’ Sixty-sixth Series of Meetings

Health, Intellectual Property and Biodiversity Programme, South Centre

This report reviews the key discussions and outcomes of the 66th Series of Meetings of the World Intellectual Property Organization (WIPO) Assemblies held in July 2025. The Assemblies addressed important governance, oversight, and norm-setting issues. Key developments included the launch of the process to appoint a new Director General, decisions on committee compositions and approval of the 2026/27 Program and Budget. Developing countries advocated for more inclusive participation in governance, balanced priority setting on norm-setting work, and stronger implementation of the Development Agenda.

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Policy Brief 147, 24 October 2025

Reeling Towards Termination: Assessing the WTO Agreement on Fisheries Subsidies and the Future of Fisheries Disciplines

By Vahini Naidu

The WTO Agreement on Fisheries Subsidies (AFS, “Fish 1”) entered into force on 15 September 2025, introducing new disciplines on subsidies linked to illegal, unreported and unregulated fishing, overfished stocks, and certain high seas activities. While celebrated as a landmark achievement, the Agreement is partial in scope, omitting the broader category of capacity-enhancing subsidies that drive overcapacity and fish stock depletion. Its obligations rely on national determinations and extensive notifications that may prove burdensome for developing Members while allowing major subsidisers to retain flexibility. The unprecedented termination clause in Article 12 ties the Agreement’s survival to the adoption of additional “comprehensive disciplines,” underscoring both the fragility of the current outcome and the need for continued negotiations. The experience of Fish 1 reveals significant lessons for the proposed WTO reform, including the importance of reviewable and time-bound rules, the risks of imbalanced sustainability provisions, and the institutional weaknesses of restricted negotiating processes.

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South Centre Statement on UNCTAD XVI Conference, 23 October 2025

South Centre Statement on UNCTAD XVI Conference “Shaping the Future: Driving Economic Transformation for Equitable, Inclusive and Sustainable Development”

 23 October 2025, Geneva, Switzerland

At UNCTAD XVI, the South Centre reaffirmed that an equitable and effective multilateral system must reflect the right of developing countries to participate in and shape the rules of global economic governance, while preserving their policy space and data sovereignty. The success of the XVI Conference will be judged by the extent to which its outcome reaffirms the organisation’s development mission and its unique role in shaping a fairer global economic order.

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