Analysis of the European Union Proposal on the Pandemic Agreement Annex dated 17 October 2025
South Centre
This note is prepared to provide South Centre Member States and other developing country delegations with analytical comments on the proposal of the European Union (EU) on the Annex to the Pandemic Agreement, implementing the Pathogen Access and Benefit Sharing (PABS) System as established in Article 12. The note begins with general commentary on the proposal, followed by detailed analysis of the EU proposal text, which is marked in red below the transcribed text.
South Centre Statement submitted to Session Three: A Fair and a Just Future for All:Critical Minerals; Decent Work; Artificial Intelligence
Dr. Carlos Correa, South Centre Executive Director, highlighted at the G20 Leaders’ Summit that while the world is transitioning to a critical mineral-intensive future, resource-rich poor countries are stuck at the bottom of the value chain. On AI, he stressed that the United Nations should continue to play an important role in shaping the international AI governance.
South Centre Statement submitted to Session One: Inclusive and sustainable economic growth leaving no one behind: Building our economies; the role of trade; financing for development and thedebt burden
South Centre Executive Director, Dr. Carlos Correa, spoke at the G20 Leaders’ Summit, congratulating South Africa’s successful G20 Presidency and stressing that any reform of the WTO should be development oriented & preserve S&DT.
Promoting a Symbiotic Relationship Between Trade Policy and Climate Action
By Vahini Naidu
This paper is based on remarks delivered in the lead up to COP30. It outlines how African countries are working to align trade, climate action, and development priorities through early transparency on climate-related trade measures, technology transfer, and the protection of policy space for green industrialisation. It also highlights the growing focus on critical minerals, the rise of unilateral climate-related trade measures, and the need to bring scattered initiatives into a coherent multilateral framework that supports fair and sustainable outcomes.
Participation of South Centre Member Countries in the WHO GLASS: Progress and Gaps in AMR Surveillance and Stewardship Efforts
By Dr. Rasha Abdelsalam Elshenawy
This study highlights antimicrobial resistance (AMR) surveillance challenges in LMICs, focusing on the 55 South Centre Member States’ enrolment in the WHO Global Antimicrobial Resistance and Use Surveillance System (GLASS). Despite progress since its 2016 launch, significant gaps persist: only 60 percent of South Centre Member States report AMR surveillance to GLASS, and just 38 percent report antimicrobial use (AMU) data to GLASS. The COVID-19 pandemic substantially disrupted surveillance activities, with rates declining from 2020-2021 compared to pre-COVID-19 pandemic levels. Digital infrastructure, such as mobile reporting tools, cloud-based systems, and interactive dashboards, offers significant opportunities to strengthen AMR surveillance in resource-limited settings. The study recommends a holistic and phased approach for South Centre Member States, including developing integrated national AMR action plans with realistic implementation timelines, investing in laboratory and workforce development, establishing interoperable digital infrastructure, and strengthening regional collaboration mechanisms. By systematically addressing core surveillance challenges while strategically incorporating digital innovations where appropriate, countries can develop resilient monitoring systems that support effective stewardship, protect national populations, and contribute to global health security by preserving antimicrobial effectiveness for future generations.
The Role of Advisory Opinions in Shaping International Climate Change Law
By Daniel Uribe Terán
This policy brief analyses how advisory opinions (AOs) from the International Court of Justice (ICJ), the International Tribunal for the Law of the Sea (ITLOS), and the Inter-American Court of Human Rights (IACtHR) are fundamentally reshaping international climate law. These AOs are crystallising States’ climate commitments, transforming them from voluntary political pledges into binding legal obligations grounded in customary international law and human rights. This judicial shift establishes stringent, science-based due diligence standards, confirms State responsibility for harm, and provides a powerful legal foundation for accountability and reparation.
From Fragmentation to Impact: Strengthening Southern Agency in Global AI Governance
By Vahini Naidu and Danish
Artificial Intelligence (AI) is transforming production, trade and governance systems, yet global regulatory efforts remain fragmented and uneven. The multiplicity of forums, frameworks and initiatives, from UN processes to plurilateral and trade-centred mechanisms, has produced overlapping agendas and resulted in diminished participation from global South stakeholders. For developing countries, the challenge is to engage meaningfully in global AI governance while preserving national policy space and advancing sustainable development priorities.
This policy brief examines the evolving landscape of AI governance, focusing on its institutional fragmentation and the competing conceptions of regulation advanced through the UN, G20, BRICS, and other fora. It argues that coherent, development-oriented AI governance requires strengthening UN-anchored processes and linking AI regulation to industrial policy, innovation systems and data sovereignty. The brief concludes that inclusive, sustainable and responsible AI governance should support governments in enhancing their capacities to harness AI and emerging technologies to shape their digital transformation.
Leveraging the ICJ Opinion to Secure a Just Climate Future for the South during COP30
By Daniel Uribe Terán
The 30th Conference of the Parties (COP30) in Belém converges with the recent International Court of Justice (ICJ) Advisory Opinion on Climate Change, creating a critical inflexion point for global climate action. This policy brief analyses how the ICJ Opinion has the potential to reframe climate commitments, transforming them from political aspirations into legally binding obligations. The Opinion establishes objective standards for ‘due diligence’, integrates the CBDR-RC principle as a legal criterion for ambition, and inextricably links climate action with human rights. The ICJ Opinion confirms that a breach of these obligations triggers a duty of ‘full reparation.’ This policy brief recommends a strategy for developing countries to leverage this new legal framework at COP30.
The GUIDE Framework for Evidence-based Antibiotic Prescribing
Strengthening Antimicrobial Stewardship for the Healthcare Workforce
By Dr. Rasha Abdelsalam Elshenawy
Antimicrobial resistance (AMR) poses a critical threat to global health security, with inappropriate antibiotic prescribing in hospitals driving the spread of resistant pathogens. This GUIDE Framework for Evidence-Based Antibiotic Prescribing provides a structured, five-step model designed to strengthen antimicrobial stewardship (AMS) and empower the healthcare workforce to make informed, proportionate prescribing decisions.
South Centre in collaboration with IT for Change and Center of Policy Research and Governance, with the support of the Permanent Mission of India to the UN in Geneva
Monday, 17 November 2025, 13:15 – 14:15, Palais des Nations, Room VIII, Geneva
Held in preparation for the AI Impact Summit 2026, this event will discuss how countries can work together to ensure Artificial Intelligence supports inclusive and sustainable development, strengthens national and regional capacities, and promotes equitable participation in global AI governance.
Digital businesses continue to grow and generate substantial revenue in market jurisdictions without maintaining a physical presence. They mainly rely on intangibles, user data and user engagement. International tax rules have not kept pace with these developments, leaving many jurisdictions unable to tax digital economic activity effectively. In response, countries have introduced national measures, such as Digital Services Taxes (DSTs), equalisation levies, and Significant Economic Presence (SEP) taxes, while continuing to engage in multilateral efforts. This paper examines how countries have implemented such measures. The study applies structured case studies of Colombia, India, Kenya, Nepal, Nigeria, and Tanzania. It analyzes the countries’ legal frameworks, administrative practices, and revenue outcomes, while also identifying shared features and key differences in implementation approaches. The paper explores the conceptual foundations and theoretical justifications for taxing digital revenues at source, highlighting the limitations of current profit allocation rules that overlook the role of the market. Drawing from these country experiences, the study develops a peer learning framework based on emerging best practices while recognizing the challenges in implementation. The study then proposes pathways for harmonizing digital tax measures and outlines essential design elements to inform the development of the early protocol on the taxation of cross border services (which includes digital services) under the United Nations Framework Convention on International Tax Cooperation.
Report on Compulsory Licensing Provisions in the National Patent Legislation of 15 Middle-Income Countries:
A Content Analysis and Recommendations
A Report of the Global Economic Governance Initiative of the Boston University Global Development Policy Center
Published by the South Centre and the Global Economic Governance Initiative of Boston University Global Development Policy Center
This study examines compulsory licensing laws in 15 middle-income countries often excluded from voluntary licenses & finds significant untapped policy space to advance access to affordable medicines. It highlights best practices & makes key recommendations to improve patent laws for the use of this important TRIPS flexibility.
