Designing an Independent Panel onEvidence for Action on Antimicrobial Resistance: Lessons from Selected Bodies in Global Health, Climate Change and Biodiversity
By Viviana Munoz Tellez and Francesca Chiara
This paper proposes a framework for designing an Independent Panel on Evidence for Action on Antimicrobial Resistance (IPEA), responding to the 2025 United Nations General Assembly mandate. Through a comparative analysis of selected international scientific advisory bodies, we identify the panel’s mandate as the foundational element that will critically shape its composition, scope, deliverables, and governance structure. Our framework addresses key domains of credibility, scientific integrity, authority, policy relevance, and sustainability while establishing equity as a fundamental design principle—not merely ensuring low and middle-income country (LMIC) participation but designing the IPEA to address existing imbalances in antimicrobial resistance (AMR) evidence production and dissemination. We analyse potential mandate options, from evidence synthesis to policy recommendations, highlighting the importance of defining a unique and complementary role for IPEA within the existing AMR governance landscape to avoid duplication and maximize impact on global AMR response.
WTO Reform: Facilitator’s Report on Initial Consultations (JOB/GC/445)
Commentary, 9 July 2025
By Vahini Naidu, Trade for Development Programme, South Centre
This commentary provides a critical analysis of the Facilitator’s Report on Initial Consultations on WTO Reform, highlighting the absence of a shared reform objective, the fragmentation of issues, and the risks posed to developing country priorities, particularly with respect to the Special and Differential Treatment and self-designation, and the consensus-based decision-making. It examines the legal and institutional implications of current reform narratives and cautions against proposals that may entrench rather than correct systemic imbalances.
The AI Race: A Tightrope Walk Between Innovation, Inclusivity and Prosperity for All
By Daniel Uribe Terán
The intensifying global race in Artificial Intelligence (AI) forces nations to walk a tightrope, balancing the drive for rapid innovation against the imperatives of fairness, safety and inclusivity. This tension is reflected in recent high-level international summits and the diverging regulatory paradigms emerging globally, most notably between the market-driven, largely deregulatory approach of the United States and the human-centric, risk-based model favoured by the European Union. Such divergence contributes to a fragmented governance landscape, posing significant challenges for developing countries, which face the risk of marginalisation due to disparities in infrastructure, resources, and technical capacity. Some of these countries have put in place proactive strategies as they endeavour to walk the tightrope between innovation and fairness in the unfolding AI era.
South Centre Inputs on the Draft Issues Notes on the UN Framework Convention on International Tax Cooperation
11 July 2025
In preparation for the First and Second Sessions of the Intergovernmental Negotiating Committee (INC) on the United Nations Framework Convention on International Tax Cooperation (UNFCITC) to be held in August 2025, the Co-Leads of each of the three Workstreams have released Draft Issues Notes for public comments. The Issues Notes are meant to provide direction on the content of the UNFCITC and its two early protocols on services and dispute prevention and resolution.
Book Review: What Do We Know and What Should We Do About Tax Justice
By Abdul Muheet Chowdhary
The book What Do We Know and What Should We Do About Tax Justice, written by Alex Cobham, CEO of the Tax Justice Network, is an excellent summary of the state of knowledge on tax justice and provides a clear direction on what should be the goals of the tax justice movement going forward.
Policy in Practice: Implementing Antimicrobial Stewardship Post-COVID-19
Q&A and Commentary
By Dr Rasha Abdelsalam Elshenawy
This report summarises the key questions and expert commentary for the South Centre, as well as the South Centre Policy Brief on lessons from the COVID-19 pandemic, to strengthen antimicrobial stewardship and provide practical recommendations discussed during the South Centre webinar on “Strengthening Antimicrobial Stewardship: Policy Insights from COVID-19 and Future Pandemic Preparedness.”
Harnessing Open Account Trade — A Major Enabler for Illicit Financial Flows from Developing Countries
Can blockchain technology come to the rescue? Will the African Continental Free Trade Area leverage its Digital Trade Protocol?
By Yuefen Li
The current geopolitical landscape has made domestic resource mobilization an even more important imperative for developing countries. In this context, it is more urgent than ever to combat illicit financial flows (IFFs) whose staggering amount from developing countries has outstrippedthe combinedsum of official development assistance (ODA) and foreign direct investment (FDI)going into the developing world. The IFFs from the financial channel is significant, but the greater proportion ofIFFs actually stems from trade channels rather than from financial channels. It is particularly concerning that the flexibility and legitimacy of international trade have been exploited to cover IFFs. Trade mis-invoicingisthe largest component of IFFs from developing countries. A major reason for trade being used to undertake illicit, fraudulent or criminal activities is because 80%-85% of the more than US$ 24 trillion international trade is conducted via open account trade (OAT), which has minimum scrutiny as it is conducted on a bilateral basis between the importer and exporter, not transparent and with minimal involvement of the financial institutions and customs authorities. OAT payment does not require documents to prove quality, quantity and other information about the product being shipped and is made through automatic payment systems which lack the oversight provided by any third party. OAT gives trade mis-invoicing great ease, flexibility, minimal cost and minimal risk. Therefore, if the world is serious about combatting IFFs, it is urgent and imperative to close loopholes in the OAT for IFFs, making it transparent, trackable and involving third party monitoring and scrutiny. The functionalities and features of Blockchain technology (BCT), though its implementation is still nascent, can be a good candidate to make OAT more modern, transparent to regulators, traceable, more efficient and above all minimize IFFs.The goals of the African Continental Free Trade Area (AfCFTA)’sDigital Trade Protocol (DTP)includeboosting intra-African trade through unifying and harmonizing regulatory framework for Africa’s digital economy and regional trade, promoting cross-border data flows and paperless trade,and enhancing cybersecurity measures.Theexploration of Blockchain adoption to reduce OAT’s risks for IFFs and make trade more effective aligns well with DTP’s goals.
Advancing Women and Girls’ Health in a Time of Converging Crises
South Centre Briefing Session (April 2025) Report
The South Centre hosted a high-level briefing session aimed at advancing the health rights of women and girls in the face of multiple global challenges. The meeting coincided with the South Centre’s 30th anniversary and the 30th anniversary of the Beijing Declaration and Platform for Action, bringing together ambassadors, health experts, and representatives of international organisations to discuss the protection and advancement of sexual and reproductive health and rights (SRHR) in the Global South.
Sexual and Reproductive Health and Rights in the Context of International Human Rights
By Carlos Correa and Daniel Uribe
This policy brief examines the growing recognition of sexual and reproductive health and rights (SRHR) within the framework of international human rights law. It traces the evolution of this consensus through key United Nations (UN) General Assembly and Human Rights Council resolutions, foundational documents like the International Conference on Population and Development (ICPD) Programme of Action and the Beijing Platform for Action, and the interpretative work of human rights treaty bodies. These instruments increasingly affirm that SRHR are an integral component of the right to health and are essential for gender equality. However, this brief also highlights the challenges these common efforts face in line with other views, which prioritise national sovereignty in determining policies on reproductive health. The analysis highlights the tension between the evolving international human rights framework and state-centric approaches, concluding with the imperative for ongoing dialogue to solidify and implement SRHR as universal, inalienable human rights.
Reducing the Cost of Remittances – A Priority for the Global South
By Danish
Remittances are a lifeline for many households in low and middle income countries (LMICs), and have emerged as an important source of external financing for sustainable development. With over 800 million people dependent on remittances worldwide, their importance for developing and least developed countries is well established. However, the high cost of remittances remains a significant challenge, and despite global commitments to reduce these costs, progress has slowed down.
This paper thus provides an assessment of the current drivers of remittance costs and explores the relevant policy discussions and initiatives at the United Nations (UN) and Group of Twenty (G20). It further highlights the continuing challenges as well as the innovative solutions such as increasing digitalisation and development of cross-border fast payment systems in different regions of the global South. The upcoming Fourth International Conference on Financing for Development (FfD4) and G20 initiatives under South Africa’s Presidency present important opportunities for the international community to redouble its efforts and make concrete, ambitious commitments to lower the cost of remittances. Finally, the paper provides some relevant policy considerations and recommendations, especially to accelerate the implementation of existing commitments, leverage digital public infrastructure and to discourage levying of taxes on remittance flows to developing countries.
Winds of Change: The BRICS Club of Nations Chipping Away at Western Dominance
The Dawn of the New South
By Len Ishmael, PhD
This era of polycrises, a global health pandemic coupled with wars in Europe and the Middle East, against the backdrop of Great Power rivalry and climate related emergencies, has profoundly affected all countries, rich and poor alike. Disproportionately affected have been those of the Global South for whom the World Bank has cautioned a ‘decade of lost development.’ As rising geopolitical tensions fuel security concerns, the nature of economic ties between countries is changing. Several countries – spearheaded by BRICS members – have started to consider alternatives to the Western financial institutional architecture in a bid to safeguard their own interests. These measures risk fragmenting the existing global financial infrastructure and derailing benefits derived from decades of economic integration in the face of new barriers to cross border investment, commerce, and trade. Recent research shows that trade restrictions have more than tripled since 2019, financial sanctions have expanded and the geopolitical risk index has also spiked, following Russia’s invasion of Ukraine. After decades of accepting the West’s rules, there is a sense that the era of the Global South is dawning, and that Western interests are no longer de facto those of the rest of the world. It is in this milieu that the BRICS and their initiatives take on heightened economic and political significance.
Scope of Compulsory License and Government Use of Patented Medicines
To meet public health needs governments can use compulsory licenses and government use as a tool for procurement and import of patented medicines. These mechanisms are provided for in most laws worldwide. The WTO TRIPS Agreement, as reaffirmed by the Doha Declaration on TRIPS and Public Health, recognises the right of WTO members to grant compulsory licenses and their freedom to determine the grounds upon which such licenses may be granted.
This table provides information of instances of their use.
